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Artsen schrijven metronidazol voor bij bepaalde infecties door bacteriën, bijvoorbeeld infecties van de baarmoeder, de darmen, de huid en bij ernstige infecties van de mond, keel of kaak, zoals ontsteking van het tandvlees (gingivitis), de wortels van tanden en kiezen (parodontitis) of van de gehele mond (ziekte van Plaut-Vincent). Two pharmacokinetic studies with a combined oral contraceptive have been performed using multiple doses of fluconazole. There were no relevant effects on hormone level in the 50 mg fluconazole study, while at 200 mg daily, the AUCs of ethinyl estradiol and levonorgestrel were increased 40% and 24%, respectively. Thus, multiple dose use of fluconazole at these doses is unlikely to have an effect on the efficacy of the combined oral contraceptive. Side Effects
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